SubtiBank SubtiBank
Version comparison:

2017-02-27 15:02:04Sun Feb 19 2017 11:49:31 GMT+0100 (CET)

proteinLength

197

geneLength

591

Gene

Phenotypes of a mutant

essential [Pubmed|24440399], non-essential according to [Pubmed|28189581]

''[[gene|scpB]]'' mutants are not viable on complex medim that allow rapid growth, but they are viable under conditions of slow growth [Pubmed|24440399,24440393]

essential [Pubmed|24440399], non-essential according to [Pubmed|28189581]

''[[protein|scpB]]'' mutants are not viable on complex medim that allow rapid growth, but they are viable under conditions of slow growth [Pubmed|24440399,24440393]

The protein

[SW|Localization]

nucleoid (Multiple) [Pubmed|16479537]

the [SW|condensin] ([[protein|Smc]])2-[[protein|ScpA]]-[[protein|ScpB]] complex is loaded by [[protein|ParB]] to ''parS'' centromeric sites adjacent to the replication origin, travels then from the origin to the terminus at rates >50 kb per minute [Pubmed|28154080,24440393,23475963]

nucleoid (Multiple) [Pubmed|16479537]

the [SW|condensin] ([[protein|Smc]])2-[[protein|ScpA]]-[[protein|ScpB]] complex forms two bipolar assemblies on the chromosome, one in each cell half, localization depends on [SW|Spo0J] [Pubmed|24440393,23475963]

Expression and Regulation

[[this]]

[SW|Categories] containing this gene/protein

[SW|DNA condensation/ segregation], [SW|essential genes]

The protein

[SW|Interactions]

part of the [SW|condensin] complex [Pubmed|24440399,24440393]

forms dimers [Pubmed|22385855]

[[protein|ScpB]]-[[protein|Smc]] [Pubmed|22385855,12100548], this interaction takes place only in the presence of [[protein|ScpA]] [Pubmed|22385855]

[[protein|ScpA]]-[[protein|ScpB]] [Pubmed|23353789,12100548]

Expression and Regulation

Operon

''[[protein|scpA]]-[[protein|scpB]]-[[protein|ypuI]]'' [Pubmed|7934830]

Expression and Regulation

Regulation

[[protein|RelA]] dependent downregulation (Class I) during stringent response [Pubmed|11948165]